Xi Li Selected Research

Tyrosine Kinase Inhibitors

4/2024	DB-1310, an ADC comprised of a novel anti-HER3 antibody conjugated to a DNA topoisomerase I inhibitor, is highly effective for the treatment of HER3-positive solid tumors.
9/2023	Efficacy of epidermal growth factor receptor tyrosine kinase inhibitor in the treatment of patients with nonsmall cell lung cancer.
1/2022	Application of ddPCR in detection of the status and abundance of EGFR T790M mutation in the plasma samples of non-small cell lung cancer patients.
9/2021	A novel GHR-ALK fusion gene in a patient with metastatic lung adenocarcinoma and its response to crizotinib: a case report.
12/2017	The prognostic role of EGFR-TKIs for patients with advanced non-small cell lung cancer.
11/2015	Subsequent treatment of epidermal growth factor receptor-tyrosine kinase inhibitor failure in patients with advanced lung adenocarcinoma.
10/2015	[Detection and Analysis of EGFR and KRAS Mutations  in the Patients with Lung Squamous Cell Carcinomas].
1/2014	Efficacy and predictors of EGFR tyrosine kinase inhibitors in Chinese advanced lung adenocarcinoma: analyses of 253 cases from a single institute.
11/2013	Comparison of EGFR signaling pathway somatic DNA mutations derived from peripheral blood and corresponding tumor tissue of patients with advanced non-small-cell lung cancer using liquidchip technology.

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Xi Li Research Topics

Disease

177	Neoplasms (Cancer) 05/2024 - 09/2002
51	Inflammation (Inflammations) 05/2024 - 03/2007
47	Infections 01/2024 - 08/2007
45	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 02/2024 - 06/2004
29	Breast Neoplasms (Breast Cancer) 04/2024 - 06/2006
25	Alzheimer Disease (Alzheimer's Disease) 04/2024 - 02/2010
25	Lung Neoplasms (Lung Cancer) 04/2024 - 05/2005
23	Cardiovascular Diseases (Cardiovascular Disease) 05/2024 - 05/2011
22	Myocardial Infarction 12/2021 - 06/2013
20	Hepatocellular Carcinoma (Hepatoma) 01/2024 - 06/2010
20	Neoplasm Metastasis (Metastasis) 01/2023 - 06/2006
16	Obesity 04/2024 - 09/2006
16	Fibrosis (Cirrhosis) 03/2024 - 11/2016
16	Wounds and Injuries (Trauma) 11/2023 - 12/2014
15	Insulin Resistance 05/2024 - 06/2006
13	Type 2 Diabetes Mellitus (MODY) 05/2024 - 08/2014
13	Ovarian Neoplasms (Ovarian Cancer) 01/2023 - 01/2013
12	Hypertension (High Blood Pressure) 01/2024 - 04/2005
12	Adenocarcinoma of Lung 07/2022 - 01/2014
12	Ischemic Stroke 01/2022 - 08/2010
11	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2023 - 09/2006
11	Carcinoma (Carcinomatosis) 07/2020 - 04/2002
10	Liver Diseases (Liver Disease) 05/2024 - 11/2011
10	Non-alcoholic Fatty Liver Disease 03/2024 - 12/2015
10	COVID-19 01/2024 - 01/2020
10	Hypoxia (Hypoxemia) 11/2023 - 09/2011
10	Parkinson Disease (Parkinson's Disease) 08/2023 - 01/2018
10	Melanoma (Melanoma, Malignant) 01/2023 - 06/2013
10	Body Weight (Weight, Body) 01/2022 - 05/2014
10	Liver Cirrhosis (Hepatic Cirrhosis) 01/2022 - 05/2006
9	Coronary Disease (Coronary Heart Disease) 04/2024 - 05/2011
9	Sepsis (Septicemia) 01/2023 - 06/2012
9	Colonic Neoplasms (Colon Cancer) 01/2023 - 08/2007
9	Carcinogenesis 01/2020 - 10/2007
8	Reperfusion Injury 01/2024 - 03/2005
8	Necrosis 01/2023 - 05/2006
7	Stroke (Strokes) 04/2024 - 08/2010
7	Stomach Neoplasms (Stomach Cancer) 12/2023 - 05/2017
7	Ischemia 11/2023 - 03/2005
7	Bacterial Infections (Bacterial Infection) 01/2023 - 02/2010
6	Bites and Stings (Sting) 01/2024 - 01/2021
6	Lymphoma (Lymphomas) 01/2024 - 01/2021
6	Pancreatic Neoplasms (Pancreatic Cancer) 01/2024 - 05/2012
6	Chronic Hepatitis B 10/2023 - 08/2007
6	Mitochondrial Diseases (Mitochondrial Disease) 11/2022 - 01/2016

Drug/Important Bio-Agent (IBA)

61	Proteins (Proteins, Gene)FDA Link 01/2024 - 09/2006
40	Biomarkers (Surrogate Marker)IBA 01/2024 - 01/2015
25	MicroRNAs (MicroRNA)IBA 11/2023 - 03/2014
19	Glucose (Dextrose)FDA LinkGeneric 04/2024 - 08/2007
19	PlatinumIBA 02/2023 - 06/2004
18	Messenger RNA (mRNA)IBA 11/2023 - 06/2006
17	ErbB Receptors (EGF Receptor)IBA 04/2024 - 11/2013
17	EnzymesIBA 01/2024 - 12/2005
16	Long Noncoding RNAIBA 04/2023 - 06/2016
16	DNA (Deoxyribonucleic Acid)IBA 01/2023 - 02/2003
14	Amyloid (Amyloid Fibrils)IBA 01/2024 - 08/2014
14	LigandsIBA 01/2023 - 04/2011
13	AntigensIBA 02/2024 - 05/2010
12	Cisplatin (Platino)FDA LinkGeneric 04/2024 - 06/2004
12	Reactive Oxygen Species (Oxygen Radicals)IBA 02/2023 - 09/2011
11	Indicators and Reagents (Reagents)IBA 01/2024 - 07/2011
11	Therapeutic UsesIBA 11/2023 - 01/2009
10	Immune Checkpoint InhibitorsIBA 04/2024 - 01/2021
10	Peptides (Polypeptides)IBA 01/2024 - 02/2010
10	RNA (Ribonucleic Acid)IBA 01/2023 - 09/2015
9	Tyrosine Kinase InhibitorsIBA 04/2024 - 11/2013
9	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2020 - 06/2006
8	AutoantibodiesIBA 05/2024 - 11/2011
8	LipidsIBA 03/2024 - 10/2019
8	ginsenoside Rg1IBA 01/2024 - 10/2006
8	InterferonsIBA 12/2023 - 08/2013
8	CytokinesIBA 11/2023 - 05/2011
8	Carbapenems (Carbapenem Antibiotics)IBA 06/2023 - 01/2018
8	Interleukin-6 (Interleukin 6)IBA 01/2023 - 10/2009
8	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 01/2020 - 02/2011
7	CholesterolIBA 05/2024 - 01/2015
7	Insulin (Novolin)FDA Link 01/2024 - 12/2014
7	Immunoglobulin G (IgG)IBA 01/2024 - 05/2011
7	MetalsIBA 11/2023 - 01/2017
7	Anti-Bacterial Agents (Antibiotics)IBA 01/2023 - 01/2014
7	VaccinesIBA 11/2021 - 01/2009
7	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/2021 - 03/2007
7	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2020 - 08/2010
7	EndostatinsIBA 02/2005 - 04/2002
6	AntibodiesIBA 04/2024 - 05/2010
6	Circular RNAIBA 01/2024 - 03/2018
6	Adenosine Triphosphate (ATP)IBA 12/2023 - 03/2012
6	Transcription Factors (Transcription Factor)IBA 11/2023 - 02/2011
6	Aspartate Aminotransferases (Aspartate Transaminase)IBA 10/2023 - 05/2006
6	AntioxidantsIBA 02/2023 - 03/2005

Therapy/Procedure

109	Therapeutics 04/2024 - 11/2002
50	Drug Therapy (Chemotherapy) 01/2024 - 06/2004
21	Immunotherapy 05/2024 - 07/2010
11	Secondary Prevention 01/2020 - 08/2010
9	Length of Stay 01/2024 - 04/2010
8	Percutaneous Coronary Intervention 01/2023 - 03/2014
8	Transcatheter Aortic Valve Replacement 11/2022 - 01/2020
7	Chinese Traditional Medicine (Traditional Chinese Medicine) 01/2024 - 10/2006
7	Radiotherapy 01/2022 - 09/2014
6	Lasers (Laser) 12/2023 - 01/2018